A fluid conduit coupling assembly has a depressible latch mechanism that secures a first fluid conduit to a second fluid conduit via a first coupler and a second coupler. The first coupler connects to the first fluid conduit and the second coupler connects to the second fluid conduit. The depressible latch mechanism is formed by a pair of cantilevered buttons disposed in symmetrically opposed positions on one of the couplers. The cantilevered buttons have engagement lips that extend distally with catches that extend radially outward to engage a ridge formed on an interior wall of the opposing coupler. Fluid ports within the couplers interface when the couplers connect to provide fluid flow between the first and second conduits. Valves may be disposed in each of the couplers to arrest fluid flow when the couplers are detached and automatically open to allow fluid to flow when the couplers are connected.