An axle assembly includes a non-rotating component and a wheel hub supported for rotation relative to the non-rotating component about an axis. The wheel hub includes a hub air passage that has a hub inlet and a hub outlet to be fluidly connected to at least one tire. An air chamber is formed at least in part between the non-rotating component and the wheel hub. The air chamber receives air flow from an air source and directs air flow into the hub inlet. A seal assembly engages the wheel hub to seal the air chamber.