Invention Grant
- Patent Title: Subtypes of humanized antibody against interleuken-6 receptor
- Patent Title (中): 人白细胞介素-6受体人源化抗体亚型
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Application No.: US10593786Application Date: 2005-03-24
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Publication No.: US08398980B2Publication Date: 2013-03-19
- Inventor: Katsuhiro Kano , Isamu Terashima
- Applicant: Katsuhiro Kano , Isamu Terashima
- Applicant Address: JP Tokyo
- Assignee: Chugai Seiyaku Kabushiki Kaisha
- Current Assignee: Chugai Seiyaku Kabushiki Kaisha
- Current Assignee Address: JP Tokyo
- Agency: Morrison & Foerster LLP
- Priority: JP2004-087578 20040324
- International Application: PCT/JP2005/006229 WO 20050324
- International Announcement: WO2005/090405 WO 20050929
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C12P21/08 ; C07K16/00 ; C07K16/24

Abstract:
As a subtype of humanized PM-1 antibody against interleukin-6 receptor (IL-6R), there is provided antibody sub-type (1) whose one heavy chain C terminus consists of Pro-NH2 (447). As another subtype of humanized PM-1 antibody against interleukin-6 receptor (IL-6R), there is provided antibody subtype (2) whose both heavy chain C termini consist of Pro-NH2 (447). Furthermore, there are provided pharmaceutical compositions comprising these.
Public/Granted literature
- US20100247523A1 Subtypes of humanized antibody against interleuken-6 receptor Public/Granted day:2010-09-30
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