Invention Grant
- Patent Title: Heteropolynucleotide duplexes with purine—purine base pairing
- Patent Title (中): 杂多核苷酸双链体与嘌呤 - 嘌呤碱基配对
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Application No.: US12521012Application Date: 2007-12-21
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Publication No.: US08399194B2Publication Date: 2013-03-19
- Inventor: Maria Albalos , Thomas Battersby , Edward Brooks , Michel Friesenhahn
- Applicant: Maria Albalos , Thomas Battersby , Edward Brooks , Michel Friesenhahn
- Applicant Address: US NY Tarrytown
- Assignee: Siemens Healthcare Diagnostics Inc.
- Current Assignee: Siemens Healthcare Diagnostics Inc.
- Current Assignee Address: US NY Tarrytown
- International Application: PCT/US2007/088617 WO 20071221
- International Announcement: WO2008/083090 WO 20080710
- Main IPC: C12Q1/68
- IPC: C12Q1/68
Abstract:
The present invention relates to stable anti-parallel heteropolynucleotide duplexes, comprising a plurality of complementary purine-purine nucleobase dyads, wherein the nucleobase is coupled to a pentose sugar backbone. The present invention further relates to methods of hybridizing two heteropolynucleotide molecules to form such purine-purine nucleobase dyads, as well as kits and solid supports comprising such purine-purine nucleobase dyads.
Public/Granted literature
- US20100190972A1 Heteropolynucleotide Duplexes With Purine-Purine Base Pairing Public/Granted day:2010-07-29
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