Invention Grant
US08399217B2 High density growth of T7 expression strains with auto-induction option
有权
具有自动诱导选择的T7表达菌株的高密度生长
- Patent Title: High density growth of T7 expression strains with auto-induction option
- Patent Title (中): 具有自动诱导选择的T7表达菌株的高密度生长
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Application No.: US11741282Application Date: 2007-04-27
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Publication No.: US08399217B2Publication Date: 2013-03-19
- Inventor: F. William Studier
- Applicant: F. William Studier
- Applicant Address: US NY Upton
- Assignee: Brookhaven Science Associates, LLC
- Current Assignee: Brookhaven Science Associates, LLC
- Current Assignee Address: US NY Upton
- Agent Dorene M. Price
- Main IPC: C12N15/09
- IPC: C12N15/09 ; C07H21/04
Abstract:
A method for promoting and suppressing auto-induction of transcription of a cloned gene 1 of bacteriophage T7 in cultures of bacterial cells grown batchwise is disclosed. The transcription is under the control of a promoter whose activity can be induced by an exogenous inducer whose ability to induce said promoter is dependent on the metabolic state of said bacterial cells.
Public/Granted literature
- US20070212782A1 High Density Growth of T7 Expression Strains with Auto-Induction Option Public/Granted day:2007-09-13
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