Invention Grant
- Patent Title: Production of polyunsaturated fatty acids in oleaginous yeasts
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Application No.: US12469467Application Date: 2009-05-20
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Publication No.: US08399242B2Publication Date: 2013-03-19
- Inventor: Stephen K. Picataggio , Narendra S. Yadav , Quinn Qun Zhu
- Applicant: Stephen K. Picataggio , Narendra S. Yadav , Quinn Qun Zhu
- Applicant Address: US DE Wilmington
- Assignee: E I du Pont de Nemours and Company
- Current Assignee: E I du Pont de Nemours and Company
- Current Assignee Address: US DE Wilmington
- Main IPC: C12N1/19
- IPC: C12N1/19 ; C12Q1/68
Abstract:
The present invention relates to methods for the production of ω-3 and/or ω-6 fatty acids in oleaginous yeast. Thus, desaturases and elongases able to catalyze the conversion of linoleic acid (LA) to γ-linolenic acid (GLA); α-linoleic acid (ALA) to stearidonic acid (STA); GLA to dihomo-γ-linoleic acid (DGLA); STA to eicosatetraenoic acid (ETA); DGLA to arachidonic acid (ARA); ETA to eicosapentaenoic acid (EPA); DGLA to ETA; EPA to docosapentaenoic acid (DPA); and ARA to EPA have been introduced into the genome of Yarrowia for synthesis of ARA and EPA.
Public/Granted literature
- US20090233346A1 PRODUCTION OF POLYUNSATURATED FATTY ACIDS IN OLEAGINOUS YEASTS Public/Granted day:2009-09-17
Information query
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