Invention Grant
- Patent Title: Monosebacate of pyrazole derivative
- Patent Title (中): 吡唑衍生物单癸二酸酯
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Application No.: US12810476Application Date: 2008-12-24
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Publication No.: US08399418B2Publication Date: 2013-03-19
- Inventor: Hideki Takeuchi , Eiji Tsuru
- Applicant: Hideki Takeuchi , Eiji Tsuru
- Applicant Address: JP Nagano
- Assignee: Kissei Pharmaceutical Co., Ltd.
- Current Assignee: Kissei Pharmaceutical Co., Ltd.
- Current Assignee Address: JP Nagano
- Agency: Sughrue Mion, PLLC
- Priority: JP2007-337985 20071227
- International Application: PCT/JP2008/073405 WO 20081224
- International Announcement: WO2009/084531 WO 20090709
- Main IPC: C07H17/02
- IPC: C07H17/02 ; A61K31/7056 ; A61P3/10

Abstract:
The present invention provides a novel form of 3-(3-{4-[3-(β-D-glucopyranosyloxy)-5-isopropyl-1H-pyrazol-4-ylmethyl]-3-methylphenoxy}propylamino)-2,2-dimethylpropionamide with improved storage stability. Since bis[3-(3-{4-[3-(β-D-glucopyranosyloxy)-5-isopropyl-1H-pyrazol-4-ylmethyl]-3-methylphenoxy}propylamino)-2,2-dimethylpropionamide]monosebacate has extremely excellent storage stability, it is useful as a drug substance. Furthermore, it shows an extremely good crystalline property and can be purified by a convenient method, and therefore is suitable for the industrial preparation.
Public/Granted literature
- US20100279962A1 MONOSEBACATE OF PYRAZOLE DERIVATIVE Public/Granted day:2010-11-04
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