Invention Grant
US08399423B2 Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response
有权
免疫调节寡核苷酸(IRO)化合物调节基于类似受体的免疫应答
- Patent Title: Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response
- Patent Title (中): 免疫调节寡核苷酸(IRO)化合物调节基于类似受体的免疫应答
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Application No.: US12244199Application Date: 2008-10-02
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Publication No.: US08399423B2Publication Date: 2013-03-19
- Inventor: Ekambar Kandimalla , Daqing Wang , Yukui Li , Dong Yu , FuGang Zhu , Lakshmi Bhagat , Sudhir Agrawal
- Applicant: Ekambar Kandimalla , Daqing Wang , Yukui Li , Dong Yu , FuGang Zhu , Lakshmi Bhagat , Sudhir Agrawal
- Applicant Address: US MA Cambridge
- Assignee: Idera Pharmaceuticals, Inc.
- Current Assignee: Idera Pharmaceuticals, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Wood, Phillips, Katz, Clark & Mortimer
- Main IPC: A61K48/00
- IPC: A61K48/00 ; C12N15/11

Abstract:
The invention provides the use of immune regulatory oligonucleotides (IRO) as antagonist of TLRs in the prevention and treatment of a disease caused by a pathogen, for example, a DNA or RNA virus.
Public/Granted literature
- US20090098063A1 IMMUNE REGULATORY OLIGONUCLEOTIDE (IRO) COMPOUNDS TO MODULATE TOLL-LIKE RECEPTOR BASED IMMUNE RESPONSE Public/Granted day:2009-04-16
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