Invention Grant
- Patent Title: Bicyclic heterocycles, medicaments containing said compounds, use thereof, and method for production of same
- Patent Title (中): 双环杂环,含有所述化合物的药物,其用途及其制备方法
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Application No.: US12513731Application Date: 2007-11-03
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Publication No.: US08399461B2Publication Date: 2013-03-19
- Inventor: Frank Himmelsbach , Birgit Jung
- Applicant: Frank Himmelsbach , Birgit Jung
- Applicant Address: DE Ingelheim am Rhein
- Assignee: Boehringer Ingelheim International GmbH
- Current Assignee: Boehringer Ingelheim International GmbH
- Current Assignee Address: DE Ingelheim am Rhein
- Agent Michael P. Morris; Edward S. Lazer
- Priority: EP06123820 20061110
- International Application: PCT/EP2007/061842 WO 20071103
- International Announcement: WO2008/055854 WO 20080515
- Main IPC: A61K31/517
- IPC: A61K31/517 ; A61K31/5377 ; A61K31/497 ; C07D239/94 ; C07D413/12 ; C07D403/12

Abstract:
The present invention relates to bicyclic heterocycles of general formula the tautomers, the stereoisomers, the mixtures and the salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids which have valuable pharmacological properties, particularly an inhibitory effect on signal transduction mediated by tyrosine kinases, the use thereof for treating diseases, particularly tumoral diseases, as well as benign prostatic hyperplasia (BPH), diseases of the lungs and respiratory tract, and the preparation thereof.
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