Invention Grant
US08399494B2 2,5-disubstituted phenyl carboxamide orexin receptor antagonists
失效
2,5-二取代苯基甲酰胺食欲素受体拮抗剂
- Patent Title: 2,5-disubstituted phenyl carboxamide orexin receptor antagonists
- Patent Title (中): 2,5-二取代苯基甲酰胺食欲素受体拮抗剂
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Application No.: US13126620Application Date: 2009-10-26
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Publication No.: US08399494B2Publication Date: 2013-03-19
- Inventor: Jeffrey M. Bergman , Paul J. Coleman , Anthony J. Roecker , John D. Schreier
- Applicant: Jeffrey M. Bergman , Paul J. Coleman , Anthony J. Roecker , John D. Schreier
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent J. Eric Thies; Gerard M. Devlin
- International Application: PCT/US2009/061990 WO 20091026
- International Announcement: WO2010/051237 WO 20100506
- Main IPC: A01N43/40
- IPC: A01N43/40 ; A61K31/44
Abstract:
The present invention is directed to 2,5-disubstituted phenyl carboxamide compounds which are antagonists of orexin receptors, and which are useful in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which orexin receptors are involved.
Public/Granted literature
- US20110207747A1 2,5-Disubstituted Phenyl Carboxamide Orexin Receptor Antagonists Public/Granted day:2011-08-25
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