Invention Grant
- Patent Title: Immunoglobulin insertions, deletions, and substitutions
- Patent Title (中): 免疫球蛋白插入，缺失和取代
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Application No.: US13336907Application Date: 2011-12-23
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Publication No.: US08399618B2Publication Date: 2013-03-19
- Inventor: Gregory Alan Lazar , Bassil I. Dahiyat , Wei Dang , Sher Bahadur Karki , Omid Vafa
- Applicant: Gregory Alan Lazar , Bassil I. Dahiyat , Wei Dang , Sher Bahadur Karki , Omid Vafa
- Applicant Address: US CA Monrovia
- Assignee: Xencor, Inc.
- Current Assignee: Xencor, Inc.
- Current Assignee Address: US CA Monrovia
- Agency: Morgan, Lewis & Bockius LLP
- Main IPC: C07K16/00
- IPC: C07K16/00 ; C07K1/00 ; C12P21/08 ; A61K39/395 ; A61K39/40 ; A61K39/42 ; C07K17/00
Abstract:
An Fc variant of a parent Fc polypeptide, wherein said Fc variant exhibits altered binding to one or more FcγRs, wherein said Fc variant comprises at least one amino acid insertion in the Fc region of said parent Fc polypeptide.
Public/Granted literature
- US20120225058A1 NOVEL IMMUNOGLOBULIN INSERTIONS, DELETIONS, AND SUBSTITUTIONS Public/Granted day:2012-09-06
Information query
