Invention Grant
US08399691B2 Method for resolution of a mixture of pinocembrin optical isomers, especially a pinocembrin racemate
有权
用于分离丝裂霉素光学异构体的混合物的方法，特别是磷胆酸外消旋物
- Patent Title: Method for resolution of a mixture of pinocembrin optical isomers, especially a pinocembrin racemate
- Patent Title (中): 用于分离丝裂霉素光学异构体的混合物的方法，特别是磷胆酸外消旋物
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Application No.: US12741143Application Date: 2008-11-07
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Publication No.: US08399691B2Publication Date: 2013-03-19
- Inventor: Song Wu , Guanhua Du , Yue Yuan , Qingyun Yang , Mei Gao , Yan Qi , Yuanfeng Tong , Yuehua Wang
- Applicant: Song Wu , Guanhua Du , Yue Yuan , Qingyun Yang , Mei Gao , Yan Qi , Yuanfeng Tong , Yuehua Wang
- Applicant Address: CN CN
- Assignee: CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co. Ltd.,Institute of Materia Medica, Chinese Academy of Medical Sciences
- Current Assignee: CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co. Ltd.,Institute of Materia Medica, Chinese Academy of Medical Sciences
- Current Assignee Address: CN CN
- Agency: Schwegman Lundberg & Woessner, P.A.
- Priority: CN200710177016 20071108
- International Application: PCT/CN2008/072983 WO 20081107
- International Announcement: WO2009/067904 WO 20090604
- Main IPC: C07D311/32
- IPC: C07D311/32
Abstract:
The present invention relates to a method for resolution of a mixture of pinocembrin optical isomers, in particular a pinocembrin racemate, using a chiral primary amine or a chiral sulfinamide. The present invention also relates to a (R)-(+)-pinocembrin obtained by the method.
Public/Granted literature
- US20100261916A1 METHOD FOR RESOLUTION OF A MIXTURE OF PINOCEMBRIN OPTICAL ISOMERS, ESPECIALLY A PINOCEMBRIN RACEMATE Public/Granted day:2010-10-14
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