There is provided a sample trituration vessel that even when the sample is relatively hard, enables triturating of the sample easily and with high efficiency. The sample trituration vessel includes a tubular body having an opening at one end and having a bottom part at the other end thereof. The tubular body is furnished with a rugged portion there-inside so as to be able to meet another rugged port formed on a trituration rod. The sample trituration vessel itself can exert shearing effect on the sample. The tubular body is formed of flexible material, and upon application of external force from outside of the tubular body, the tubular body is deformed, thereby breaking down the sample held within the tubular body.