Invention Grant
- Patent Title: Compositions and methods of using chondroitinase ABCI mutants
- Patent Title (中): 使用软骨素酶ABCI突变体的组成和方法
-
Application No.: US12781762Application Date: 2010-05-17
-
Publication No.: US08404232B2Publication Date: 2013-03-26
- Inventor: Anthony O. Caggiano , Andrea Vecchione , Jennifer Iaci
- Applicant: Anthony O. Caggiano , Andrea Vecchione , Jennifer Iaci
- Applicant Address: US NY Ardsley
- Assignee: Acorda Therapeutics, Inc.
- Current Assignee: Acorda Therapeutics, Inc.
- Current Assignee Address: US NY Ardsley
- Agency: Pepper Hamilton LLP
- Main IPC: A61K38/00
- IPC: A61K38/00 ; A61K38/46 ; C12N9/88 ; C07H21/04 ; C07K1/00 ; A61M37/00
Abstract:
The present invention relates to protein and nucleic acid mutants of chondroitinase ABCI. Such chondroitinase ABCI mutant enzymes exhibit altered chondroitin lyase activity or increased resistance to inactivation from stressors including UV light or heat. Methods of using chondroitinase ABCI mutant enzymes are also provided.
Public/Granted literature
- US20110014158A1 COMPOSITIONS AND METHODS OF USING CHONDROITINASE ABCI MUTANTS Public/Granted day:2011-01-20
Information query
IPC分类:
