Invention Grant
- Patent Title: Modified live (JMSO strain) Haemophilus parasuis vaccine
- Patent Title (中): 改良活（JMSO菌株）嗜血杆菌嗜血杆菌疫苗
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Application No.: US11648390Application Date: 2006-12-28
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Publication No.: US08404253B2Publication Date: 2013-03-26
- Inventor: Simone R. Oliveira , Randy R. Simonson , Jonathan D. Mahlberg , Mark D. Titus , Tracy A. Oleson
- Applicant: Simone R. Oliveira , Randy R. Simonson , Jonathan D. Mahlberg , Mark D. Titus , Tracy A. Oleson
- Assignee: Newport Laboratories, Inc.
- Current Assignee: Newport Laboratories, Inc.
- Agency: Merial Limited
- Agent Judy Jarecki-Black; Chad Kitchen
- Main IPC: A61K39/102
- IPC: A61K39/102 ; A61K48/00 ; A01N63/00 ; A01N65/00
Abstract:
The present invention is a culture of cells of Haemophilus parasuis exhibiting attenuated pathogenicity and capable of triggering a protective immune response when administered to pigs as a live vaccine. The present invention is also a method of preparing the cell culture, a method of preparing a vaccine from the cell culture, and a live vaccine based on the cell culture. The cell culture was modified from a pathogenic parent strain by MNNG mutagenesis and was selected by complete dependence on streptomycin for growth.
Public/Granted literature
- US20100255035A1 Modified live (JMSO strain) Haemophilus parasuis vaccine Public/Granted day:2010-10-07
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