Invention Grant
US08404453B2 High affinity binding site of HGFR and methods for identification of antagonists thereof
失效
HGFR的高亲和力结合位点和鉴定其拮抗剂的方法
- Patent Title: High affinity binding site of HGFR and methods for identification of antagonists thereof
- Patent Title (中): HGFR的高亲和力结合位点和鉴定其拮抗剂的方法
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Application No.: US12465307Application Date: 2009-05-13
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Publication No.: US08404453B2Publication Date: 2013-03-26
- Inventor: Cristina Basilico , Paolo Michieli , Paolo Carminati , Paolo Maria Comoglio
- Applicant: Cristina Basilico , Paolo Michieli , Paolo Carminati , Paolo Maria Comoglio
- Applicant Address: CH Lugano
- Assignee: Metheresis Translational Research SA
- Current Assignee: Metheresis Translational Research SA
- Current Assignee Address: CH Lugano
- Agency: Nixon & Vanderhye P.C.
- Priority: EP08103958 20080514
- Main IPC: C12Q1/48
- IPC: C12Q1/48 ; G01N33/48 ; G01N33/483 ; G01N33/50 ; C07K14/71
Abstract:
Use of a polynucleotide encoding or a polypeptide comprising at least the extracellular IPT-3 and IPT-4 domains of hepatocyte growth factor receptor for the screening and/or development of pharmacologically active agents useful in the treatment of cancer, preferably a cancer with dysregulation of hepatocyte growth factor receptor.
Public/Granted literature
- US20090298079A1 HIGH AFFINITY BINDING SITE OF HGFR AND METHODS FOR IDENTIFICATION OF ANTAGONISTS THEREOF Public/Granted day:2009-12-03
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