Invention Grant
- Patent Title: Dimer VEGF antagonist formulations
- Patent Title (中): 二聚体VEGF拮抗剂制剂
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Application No.: US13343214Application Date: 2012-01-04
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Publication No.: US08404638B2Publication Date: 2013-03-26
- Inventor: Daniel Dix , Kelly Frye , Susan Kautz
- Applicant: Daniel Dix , Kelly Frye , Susan Kautz
- Applicant Address: US NY Tarrytown
- Assignee: Regeneron Pharmaceuticals, Inc.
- Current Assignee: Regeneron Pharmaceuticals, Inc.
- Current Assignee Address: US NY Tarrytown
- Agent Joseph Zahner
- Main IPC: A61K38/18
- IPC: A61K38/18 ; A61K39/00
Abstract:
Formulations of a vascular endothelial growth factor (VEGF)-specific fusion protein antagonist are provided including a pre-lyophilized formulation, a reconstituted lyophilized formulation, and a stable liquid formulation. Preferably, the fusion protein has the sequence of SEQ ID NO:4.
Public/Granted literature
- US20120101035A1 VEGF Antagonist Formulations Public/Granted day:2012-04-26
Information query
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