Invention Grant
- Patent Title: Methods of treating cancer with doxazolidine and prodrugs thereof
- Patent Title (中): 用恶唑烷治疗癌症的方法及其前药
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Application No.: US12091321Application Date: 2006-10-30
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Publication No.: US08404650B2Publication Date: 2013-03-26
- Inventor: Tad H. Koch , David J. Burkhart , Glen C. Post , Jordan W. Nafie , Brian T. Kalet , Benjamin L. Barthel , Daniel L. Rudnicki
- Applicant: Tad H. Koch , David J. Burkhart , Glen C. Post , Jordan W. Nafie , Brian T. Kalet , Benjamin L. Barthel , Daniel L. Rudnicki
- Applicant Address: US CO Denver
- Assignee: The Regents of the University of Colorado, a body corporate
- Current Assignee: The Regents of the University of Colorado, a body corporate
- Current Assignee Address: US CO Denver
- Agency: Sheridan Ross P.C.
- International Application: PCT/US2006/060367 WO 20061030
- International Announcement: WO2007/102888 WO 20070913
- Main IPC: A01N43/04
- IPC: A01N43/04 ; A61K31/70
Abstract:
The invention provides therapeutically effective compounds for the prevention and treatment of cancer and pharmaceutical compositions containing these compounds as well as methods of using and administering these compounds. The invention also includes methods of activating a prodrug of these therapeutically effective compounds by the administration of a peptide-directed targeting construct that delivers a prodrug-activating enzyme to a target activation site.
Public/Granted literature
- US20110135618A1 METHODS OF TREATING CANCER WITH DOXAZOLIDINE AND PRODRUGS THEREOF Public/Granted day:2011-06-09
Information query
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