Invention Grant
- Patent Title: Substituted heterocyclic compounds
- Patent Title (中): 取代的杂环化合物
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Application No.: US13145721Application Date: 2010-01-22
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Publication No.: US08404672B2Publication Date: 2013-03-26
- Inventor: William J. Pitts , Alaric J. Dyckman , Steven H. Spergel , Scott Hunter Watterson
- Applicant: William J. Pitts , Alaric J. Dyckman , Steven H. Spergel , Scott Hunter Watterson
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Meyers Squibb Company
- Current Assignee: Bristol-Meyers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agent Gary D. Greenblatt
- International Application: PCT/US2010/021694 WO 20100122
- International Announcement: WO2010/085582 WO 20100729
- Main IPC: A61K31/4402
- IPC: A61K31/4402 ; C07D413/14

Abstract:
Disclosed are compounds of Formula (I) or pharmaceutically acceptable salts thereof, wherein Q is R1 is cycloalkyl, heteroaryl, or heterocyclyl, each optionally substituted with one to five substituents independently selected from C1 to C6 alkyl, C1 to C4 haloalkyl, —OR4, and/or halogen; and R2, R3, R4, and n are defined herein. Also disclosed are methods of using such compounds as selective agonists for G protein-coupled receptor S1P1, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing the progression of diseases or disorders in a variety of therapeutic areas, such as vascular disease and autoimmune diseases.
Public/Granted literature
- US20120022041A1 SUBSTITUTED HETEROCYCLIC COMPOUNDS Public/Granted day:2012-01-26
Information query
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