Invention Grant
US08404681B2 Xanthones, thioxanthones and acridinones as DNA-PK inhibitors
失效
呫吨酮，噻吨酮和吖啶酮作为DNA-PK抑制剂
- Patent Title: Xanthones, thioxanthones and acridinones as DNA-PK inhibitors
- Patent Title (中): 呫吨酮，噻吨酮和吖啶酮作为DNA-PK抑制剂
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Application No.: US10550978Application Date: 2004-03-19
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Publication No.: US08404681B2Publication Date: 2013-03-26
- Inventor: James W. Halbrook , Edward A. Kesicki , Laurence E. Burgess , Stephen T. Schlachter , Charles T. Eary , Justin G. Schiro
- Applicant: James W. Halbrook , Edward A. Kesicki , Laurence E. Burgess , Stephen T. Schlachter , Charles T. Eary , Justin G. Schiro
- Applicant Address: US NY Shirley
- Assignee: Luitpold Pharmaceuticals, Inc.
- Current Assignee: Luitpold Pharmaceuticals, Inc.
- Current Assignee Address: US NY Shirley
- Agency: Wolf, Greenfield & Sacks, P.C.
- International Application: PCT/US2004/008459 WO 20040319
- International Announcement: WO2004/085418 WO 20041007
- Main IPC: A61K31/535
- IPC: A61K31/535 ; C07D413/04
Abstract:
Compound that inhibit DNA-dependent protein kinase, compositions comprising the compounds, methods of inhibiting the DNA-PK biological activity, methods of sensitizing cells the agents that cause DNA lesions, and methods of potentiating cancer treatment are disclosed.
Public/Granted literature
- US20070167441A1 Xanthones, thioxanthones and acridinones as dna-pk inhibitors Public/Granted day:2007-07-19
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