Invention Grant
US08404685B2 Dihydropyrazole derivatives as tyrosine kinase modulators for the treatment of tumors
有权
二氢吡唑衍生物作为治疗肿瘤的酪氨酸激酶调节剂
- Patent Title: Dihydropyrazole derivatives as tyrosine kinase modulators for the treatment of tumors
- Patent Title (中): 二氢吡唑衍生物作为治疗肿瘤的酪氨酸激酶调节剂
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Application No.: US12993892Application Date: 2009-04-24
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Publication No.: US08404685B2Publication Date: 2013-03-26
- Inventor: Dieter Dorsch , Oliver Schadt , Frank Stieber , Andree Blaukat
- Applicant: Dieter Dorsch , Oliver Schadt , Frank Stieber , Andree Blaukat
- Applicant Address: DE Darmstadt
- Assignee: Merck Patent Gesellschaft Mit Beschrankter Haftung
- Current Assignee: Merck Patent Gesellschaft Mit Beschrankter Haftung
- Current Assignee Address: DE Darmstadt
- Agency: Millen, White, Zelano & Branigan, P.C.
- Priority: DE102008025750 20080529
- International Application: PCT/EP2009/003030 WO 20090424
- International Announcement: WO2009/143945 WO 20091203
- Main IPC: A61K31/5377
- IPC: A61K31/5377 ; A61K31/506 ; A61K31/4245 ; C07D403/14 ; C07D401/14 ; C07D413/10 ; A61P35/00
Abstract:
Compounds of the formula I, in which R1, R2, R3, R3′, R4 and D have the meanings indicated in Claim 1, are inhibitors of tyrosine kinases, in particular Met kinase, and can be employed, inter alia, for the treatment of tumors.
Public/Granted literature
- US20110071153A1 DIHYDROPYRAZOLE DERIVATIVES AS TYROSINE KINASE MODULATORS FOR THE TREATMENT OF TUMORS Public/Granted day:2011-03-24
Information query
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