Invention Grant
- Patent Title: Nitrone compounds, process of preparation thereof, and use thereof in medicament manufacture
- Patent Title (中): 硝基化合物，其制备方法及其在药物制备中的应用
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Application No.: US12937405Application Date: 2009-04-16
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Publication No.: US08404688B2Publication Date: 2013-03-26
- Inventor: Yuqiang Wang , Jie Jiang , Pei Yu , Yewei Sun , Linda Wang , Zaijun Zhang
- Applicant: Yuqiang Wang , Jie Jiang , Pei Yu , Yewei Sun , Linda Wang , Zaijun Zhang
- Applicant Address: CN Guangzhou
- Assignee: Jinan University
- Current Assignee: Jinan University
- Current Assignee Address: CN Guangzhou
- Agency: Maschoff Brennan
- Priority: CN200810027706 20080425
- International Application: PCT/CN2009/071312 WO 20090416
- International Announcement: WO2009/129726 WO 20091029
- Main IPC: A61K31/4965
- IPC: A61K31/4965
Abstract:
The present invention provides novel nitrones, their preparation and use. The novel compounds have the following formula: I The compounds of the present invention have strong antioxidative activity, and are thrombolytic. These compounds can be used to treat and/or prevent diseases caused by overproduction of free radicals and/or formation of thrombus.
Public/Granted literature
- US20110034485A1 NITRONE COMPOUNDS, PROCESS OF PREPARATION THEREOF, AND USE THEREOF IN MEDICAMENT MANUFACTURE Public/Granted day:2011-02-10
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