Invention Grant
US08404702B2 Pharmaceutical formulations:salts of 8-[1-3,5-bis-(trifluoromethyl)phenyl)-ethoxymethyl]-8-phenyl-1,7-diaza-spiro[4.5]decan-2-one and treatment methods using the same
有权
药物制剂：8- [1-3,5-双 - （三氟甲基）苯基） - 乙氧基甲基] -8-苯基-1,7-二氮杂 - 螺[4.5]癸-2-酮的盐和使用其的处理方法
![Pharmaceutical formulations:salts of 8-[1-3,5-bis-(trifluoromethyl)phenyl)-ethoxymethyl]-8-phenyl-1,7-diaza-spiro[4.5]decan-2-one and treatment methods using the same](/docs/US/2013-03-26/US08404702B2/abs.jpg.600x600.jpg)
- Patent Title: Pharmaceutical formulations:salts of 8-[1-3,5-bis-(trifluoromethyl)phenyl)-ethoxymethyl]-8-phenyl-1,7-diaza-spiro[4.5]decan-2-one and treatment methods using the same
- Patent Title (中): 药物制剂：8- [1-3,5-双 - （三氟甲基）苯基） - 乙氧基甲基] -8-苯基-1,7-二氮杂 - 螺[4.5]癸-2-酮的盐和使用其的处理方法
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Application No.: US13184926Application Date: 2011-07-18
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Publication No.: US08404702B2Publication Date: 2013-03-26
- Inventor: Zhihui Qiu , Larisa Reyderman
- Applicant: Zhihui Qiu , Larisa Reyderman
- Applicant Address: US FL Miami
- Assignee: Opko Health, Inc.
- Current Assignee: Opko Health, Inc.
- Current Assignee Address: US FL Miami
- Agency: Choate, Hall & Stewart LLP
- Agent Brenda Herschbach Jarrell; Kristen C. Buteau
- Main IPC: A61K31/438
- IPC: A61K31/438 ; C07D219/00 ; C07D497/10
![Pharmaceutical formulations:salts of 8-[1-3,5-bis-(trifluoromethyl)phenyl)-ethoxymethyl]-8-phenyl-1,7-diaza-spiro[4.5]decan-2-one and treatment methods using the same](/abs-image/US/2013/03/26/US08404702B2/abs.jpg.150x150.jpg)
Abstract:
Pharmaceutical formulations containing salts of (5S,8S)-8-[{(1R)-1-(3,5-Bis-(trifluoromethyl)phenyl]-ethoxy}-methyl]-8-phenyl-1,7-diazaspiro[4.5]decan-2-one, represented by Formula I, are disclosed. Disclosed also are methods of treatment utilizing such dosage forms.
Public/Granted literature
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