Invention Grant
- Patent Title: Spirocyclic cyclohexane compounds
- Patent Title (中): 螺环己烷化合物
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Application No.: US12545461Application Date: 2009-08-21
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Publication No.: US08404740B2Publication Date: 2013-03-26
- Inventor: Stefan Schunk , Saskia Zemolka , Derek Saunders , Michael Gruss , Heinz Graubaum
- Applicant: Stefan Schunk , Saskia Zemolka , Derek Saunders , Michael Gruss , Heinz Graubaum
- Applicant Address: DE Aachen
- Assignee: Gruenenthal GmbH
- Current Assignee: Gruenenthal GmbH
- Current Assignee Address: DE Aachen
- Agency: Crowell & Moring LLP
- Priority: DE102007009235 20070222
- Main IPC: A61K31/35
- IPC: A61K31/35 ; A61K31/382 ; C07D335/04 ; C07D209/54

Abstract:
Spirocyclic cyclohexane compounds corresponding to formula I In which R1, R2, R3 and R5 through R10 and X have defined meanings, a process for their preparation, pharmaceutical compositions containing such compounds, and the use of such spirocyclic cyclohexane compounds in the treatment and/or inhibition of pain and other conditions mediated by the ORL-1 or the μ-opioid receptor.
Public/Granted literature
- US20100048554A1 Spirocyclic Cyclohexane Compounds Public/Granted day:2010-02-25
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