Invention Grant
- Patent Title: Isolated BRCA1 peptides and method of use
- Patent Title (中): 分离的BRCA1肽及其使用方法
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Application No.: US12849261Application Date: 2010-08-03
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Publication No.: US08404806B2Publication Date: 2013-03-26
- Inventor: Martina Buck
- Applicant: Martina Buck
- Applicant Address: US CA Oakland
- Assignee: The Regents of the University of California
- Current Assignee: The Regents of the University of California
- Current Assignee Address: US CA Oakland
- Agency: Sutherland Asbill & Brennan LLP
- Main IPC: C07K1/00
- IPC: C07K1/00 ; C07K14/00 ; A61K38/00 ; A61P35/00 ; C07H21/02 ; C07H21/04
Abstract:
The invention provides isolated peptides of a BRCA1 domain, which bind to p53 cognate DNA and stimulate transcription activities and cancer cell apoptosis. Nucleic acids encoding the peptides, and methods of expression thereof, are also provided. The invention provides pharmaceutical compositions, and methods of use thereof, for treating breast and ovarian cancer using the peptides.
Public/Granted literature
- US20100317598A1 Isolated BRCA1 Peptides and Method of Use Public/Granted day:2010-12-16
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