Invention Grant
- Patent Title: Quinoline derivatives as P13 kinase inhibitors
- Patent Title (中): 喹啉衍生物作为P13激酶抑制剂
-
Application No.: US12600745Application Date: 2008-05-16
-
Publication No.: US08404837B2Publication Date: 2013-03-26
- Inventor: Nicholas D. Adams , Joelle Lorraine Burgess , Michael Gerard Darcy , Carla A. Donatelli , Steven David Knight , Kenneth Allen Newlander , Lance Ridgers , Martha A. Sarpong , Stanley J. Schmidt
- Applicant: Nicholas D. Adams , Joelle Lorraine Burgess , Michael Gerard Darcy , Carla A. Donatelli , Steven David Knight , Kenneth Allen Newlander , Lance Ridgers , Martha A. Sarpong , Stanley J. Schmidt
- Applicant Address: US PA Philadelph
- Assignee: GlaxoSmithKline LLC
- Current Assignee: GlaxoSmithKline LLC
- Current Assignee Address: US PA Philadelph
- Agent Duke M. Fitch; Kathryn A. Lutomski; John Lemanowicz
- International Application: PCT/US2008/063819 WO 20080516
- International Announcement: WO2008/144463 WO 20081127
- Main IPC: C07D401/14
- IPC: C07D401/14 ; C07D413/14 ; C07D498/04
Abstract:
Invented is a method of inhibiting the activity/function of PI3 kinases using quinoline derivatives. Also invented is a method of treating one or more disease states selected from: autoimmune disorders, inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, allergy, asthma, pancreatitis, multiorgan failure, kidney diseases, platelet aggregation, cancer, sperm motility, transplantation rejection, graft rejection and lung injuries by the administration of quinoline derivatives.
Public/Granted literature
- US20100152112A1 QUINOLINE DERIVATIVES AS P13 KINASE INHIBITORS Public/Granted day:2010-06-17
Information query
