Embodiments of methods and systems are described that provide methods for quantifying an entity's reaction to one or more communication signals by quantifying a probabilistic relationship between the communication signal and a known relationship of an attribute to the communication signal. With this quantification, the entity's reaction can be modeled as probability distributions that can be compared to the communication signal and known relationship. With this information, an entity's reactions can be compared to an ideal algorithm that optimally integrates the known relationships and communication signals to arrive at an optimal reaction. By making this comparison between the entity's reaction and an optimal reaction, a quantitative calibration measure can be determined. The meaning of the communication signals, or relationships to an attribute, may or may not be known and in embodiments the quantification of reactions can provide an ability to estimate an unknown attribute from the communication signals.