Invention Grant
- Patent Title: Compounds for treating amyloidoses
- Patent Title (中): 用于治疗淀粉样变性的化合物
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Application No.: US12997673Application Date: 2009-06-12
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Publication No.: US08409581B2Publication Date: 2013-04-02
- Inventor: Markus Mandler , Radmila Santic , Harald Weninger , Edith Kopinits
- Applicant: Markus Mandler , Radmila Santic , Harald Weninger , Edith Kopinits
- Applicant Address: AT Vienna
- Assignee: Affiris AG
- Current Assignee: Affiris AG
- Current Assignee Address: AT Vienna
- Agency: Oblon, Spivak, McClelland, Maier & Neustadt, L.L.P.
- Priority: ATA952/2008 20080612
- International Application: PCT/AT2009/000235 WO 20090612
- International Announcement: WO2009/149485 WO 20091217
- Main IPC: A61K39/00
- IPC: A61K39/00 ; A61K38/08 ; C07K7/06
Abstract:
The present invention relates to the use of mimotopes in the treatment of β-Amyloidoses including but not limited to Alzheimer's disease, whereby said mimotopes are able to induce the in vivo formation of antibodies directed to non truncated Aβ1-40/42, and N-terminally truncated forms AβpE3-40/42, Aβ3-40/42, Aβ11-40/42, AβpE11-40/42 and Aβ14-40/42 without interfering with physiological functions of APP signalling.
Public/Granted literature
- US20110171243A1 COMPOUNDS FOR TREATING AMYLOIDOSES Public/Granted day:2011-07-14
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