Invention Grant
- Patent Title: Purified linear epitopes from cashew nuts, nucleic acids encoding therefor, and associated methods
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Application No.: US13370369Application Date: 2012-02-10
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Publication No.: US08409582B1Publication Date: 2013-04-02
- Inventor: Kenneth Roux , Shridhar Sathe , Suzanne Teuber
- Applicant: Kenneth Roux , Shridhar Sathe , Suzanne Teuber
- Applicant Address: US FL Tallahassee
- Assignee: Florida State University Research Foundation, Inc.
- Current Assignee: Florida State University Research Foundation, Inc.
- Current Assignee Address: US FL Tallahassee
- Agency: Allen, Dyer, Doppelt, Milbrath & Gilchrist, P.A.
- Main IPC: A61K39/00
- IPC: A61K39/00 ; A61K39/35 ; A61K39/36 ; A61K38/00 ; G01N33/53
Abstract:
Disclosed are major allergenic proteins in cashew nut, which are legumin-like proteins and 2S albumins. Also disclosed is a polypeptide allergen in the 7S superfamily, which includes vicilin-like and sucrose binding proteins. Several linear epitopes of the cashew nut are identified and characterized. The invention further discloses the sequence of cDNA encoding the allergenic polypeptide, the allergen being designated Ana o 1, and also describes the characterization of the expressed recombinant polypeptide and associated methods employing the polypeptide.
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