Invention Grant
- Patent Title: Method of diagnosis and kit therefor
- Patent Title (中): 诊断方法及其试剂盒
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Application No.: US12443306Application Date: 2007-09-28
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Publication No.: US08409818B2Publication Date: 2013-04-02
- Inventor: David Andrew Anderson , Robyn Elizabeth Lloyd , Suzanne Mary Crowe , Mary Louise Garcia , Alan Lee Landay
- Applicant: David Andrew Anderson , Robyn Elizabeth Lloyd , Suzanne Mary Crowe , Mary Louise Garcia , Alan Lee Landay
- Applicant Address: AU Melbourne, Victoria
- Assignee: The Macfarlane Burnet Institute for Medical Research and Public Health Limited
- Current Assignee: The Macfarlane Burnet Institute for Medical Research and Public Health Limited
- Current Assignee Address: AU Melbourne, Victoria
- Agency: Scully, Scott, Murphy & Presser, P.C.
- Priority: AU2006905393 20060928
- International Application: PCT/AU2007/001449 WO 20070928
- International Announcement: WO2008/037026 WO 20080403
- Main IPC: G01N33/00
- IPC: G01N33/00 ; G01N1/00
Abstract:
The invention provides kits and methods for detecting or monitoring the number of cells in sample. The cell comprises a cell surface associated protein (CSAP) comprising a cytoplasmic (cytosolic) and an extracellular (ecto) domain. The kit comprises: (i) a chromatographic device; and (ii) a CSAP-binding agent. The method comprises: (i) optionally contacting the sample with an agent capable of lysing or permeabilizing CSAP bearing cells; (ii) contacting the sample with a CSAP-binding agent that binds to the cytoplasmic domain of the CSAP; and (iii) directly or indirectly evaluating the level or presence of bound CSAP in the sample.
Public/Granted literature
- US20110244480A1 METHOD OF DIAGNOSIS AND KIT THEREFOR Public/Granted day:2011-10-06
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