Invention Grant
- Patent Title: TAT-utrophin as a protein therapy for dystrophinopathies
- Patent Title (中): TAT-utrophin作为肌营养不良症的蛋白质治疗
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Application No.: US12940166Application Date: 2010-11-05
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Publication No.: US08409826B2Publication Date: 2013-04-02
- Inventor: James M. Ervasti , Kevin J. Sonnemann
- Applicant: James M. Ervasti , Kevin J. Sonnemann
- Applicant Address: US WI Madison
- Assignee: Wisconsin Alumni Research Foundation
- Current Assignee: Wisconsin Alumni Research Foundation
- Current Assignee Address: US WI Madison
- Agency: DeWitt Ross & Stevens S.C.
- Agent Joseph T. Leone, Esq.
- Main IPC: C07K19/00
- IPC: C07K19/00 ; C12N15/62
Abstract:
Disclosed is a fusion protein including a full-length TAT-utrophin or an anti-dystrophinopathic fragment thereof, a method of treating dystrophinopathies (including Duchenne muscular dystrophy) using the fusion protein, a pharmaceutical composition for treating dystrophinopathies in mammals comprising the fusion protein, and nucleic acid constructs for expressing the fusion protein.
Public/Granted literature
- US20110065653A1 TAT-UTROPHIN AS A PROTEIN THERAPY FOR DYSTROPHINOPATHIES Public/Granted day:2011-03-17
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