Invention Grant
US08409831B2 Method for producing (1S,2R)-2-chloro-2-fluorocyclopropanecarboxylic acid
有权
（1S，2R）-2-氯-2-氟环丙烷羧酸的制备方法
- Patent Title: Method for producing (1S,2R)-2-chloro-2-fluorocyclopropanecarboxylic acid
- Patent Title (中): （1S，2R）-2-氯-2-氟环丙烷羧酸的制备方法
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Application No.: US13003499Application Date: 2009-07-07
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Publication No.: US08409831B2Publication Date: 2013-04-02
- Inventor: Keisuke Hatakeyama , Takashi Miki , Norihiko Hirata
- Applicant: Keisuke Hatakeyama , Takashi Miki , Norihiko Hirata
- Applicant Address: JP Tokyo JP Tokyo
- Assignee: Sumitomo Chemical Company, Limited,Daiichi Sankyo Company, Limited
- Current Assignee: Sumitomo Chemical Company, Limited,Daiichi Sankyo Company, Limited
- Current Assignee Address: JP Tokyo JP Tokyo
- Agency: Sughrue Mion, PLLC
- Priority: JP2008-182066 20080711
- International Application: PCT/JP2009/062388 WO 20090707
- International Announcement: WO2010/005003 WO 20100114
- Main IPC: C12P7/40
- IPC: C12P7/40
Abstract:
The present invention provides a method for producing (1S,2R)-2-chloro-2-fluorocyclopropanecarboxylic acid with a high yield and high selectivity. Specifically, disclosed is a method for producing (1S,2R)-2-chloro-2-fluorocyclopropanecarboxylic acid, wherein (1S)-2-chloro-2-fluorocyclopropanecarboxylic acid ester is hydrolyzed using an esterase derived from Burkholderia cepacia.
Public/Granted literature
- US20110117616A1 METHOD FOR PRODUCING (1S,2R)-2-CHLORO-2-FLUOROCYCLOPROPANECARBOXYLIC ACID Public/Granted day:2011-05-19
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