Invention Grant
- Patent Title: Stabilized activin IIB receptor polypeptides and uses thereof
- Patent Title (中): 稳定的激活素IIB受体多肽及其用途
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Application No.: US12626375Application Date: 2009-11-25
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Publication No.: US08410043B2Publication Date: 2013-04-02
- Inventor: Jeonghoon Sun , Lei-Ting Tony Tam , Mark Leo Michaels , Thomas C. Boone , Rohini Deshpande , Yue-Sheng Li , Hq Han
- Applicant: Jeonghoon Sun , Lei-Ting Tony Tam , Mark Leo Michaels , Thomas C. Boone , Rohini Deshpande , Yue-Sheng Li , Hq Han
- Applicant Address: US CA Brisbane
- Assignee: Atara Biotherapeutics, Inc.
- Current Assignee: Atara Biotherapeutics, Inc.
- Current Assignee Address: US CA Brisbane
- Agency: Fenwick & West LLP
- Main IPC: A61K38/00
- IPC: A61K38/00 ; A61K38/18
Abstract:
The present invention provides stabilized activin IIB receptor polypeptides and proteins capable of binding and inhibiting the activities of activin A, myostatin, or GDF-11. The present invention also provides polynucleotides, vectors and host cells capable of producing the stabilized polypeptides and proteins. Compositions and methods for treating muscle-wasting diseases and metabolic disorders are also provided.
Public/Granted literature
- US20100168020A1 STABILIZED RECEPTOR POLYPEPTIDES AND USES THEREOF Public/Granted day:2010-07-01
Information query
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