Invention Grant
US08410069B2 Oligoribonucleotide inhibitors of Nrf2 and methods of use thereof for treatment of cancer
有权
Nrf2的寡核苷酸抑制剂及其用于治疗癌症的方法
- Patent Title: Oligoribonucleotide inhibitors of Nrf2 and methods of use thereof for treatment of cancer
- Patent Title (中): Nrf2的寡核苷酸抑制剂及其用于治疗癌症的方法
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Application No.: US12901207Application Date: 2010-10-08
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Publication No.: US08410069B2Publication Date: 2013-04-02
- Inventor: Elena Feinstein
- Applicant: Elena Feinstein
- Applicant Address: US CA Fremont
- Assignee: Quark Pharmaceuticals, Inc.
- Current Assignee: Quark Pharmaceuticals, Inc.
- Current Assignee Address: US CA Fremont
- Agency: Cooper & Dunham LLP
- Agent John P. White
- Main IPC: C12N15/11
- IPC: C12N15/11 ; C07H21/02 ; C97H21/04
Abstract:
The invention provides novel double stranded oligoribonucleotides that inhibit the Nrf2 gene. The invention also provides a pharmaceutical composition comprising one or more such oligoribonucleotides, and a vector capable of expressing the oligoribonucleotide. The present invention also relates to methods and compositions for treating or preventing the incidence or severity of a cancerous disease, particularly various lung cancers.
Public/Granted literature
- US20110230543A1 OLIGORIBONUCLEOTIDE INHIBITORS OF NRF2 AND METHODS OF USE THEREOF FOR TREATMENT OF CANCER Public/Granted day:2011-09-22
Information query
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