Invention Grant
US08410073B2 Methods and compositions for prevention or treatment of RSV infection
失效
预防或治疗RSV感染的方法和组合物
- Patent Title: Methods and compositions for prevention or treatment of RSV infection
- Patent Title (中): 预防或治疗RSV感染的方法和组合物
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Application No.: US13359421Application Date: 2012-01-26
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Publication No.: US08410073B2Publication Date: 2013-04-02
- Inventor: Akshay Vaishnaw , Saraswathy V. Nochur , Sayda Elbashir , Muthiah Manoharan , Rachel Meyers
- Applicant: Akshay Vaishnaw , Saraswathy V. Nochur , Sayda Elbashir , Muthiah Manoharan , Rachel Meyers
- Applicant Address: US MA Cambridge
- Assignee: Alnylam Pharmaceuticals, Inc.
- Current Assignee: Alnylam Pharmaceuticals, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Fenwick & West LLP
- Main IPC: A61K31/70
- IPC: A61K31/70 ; C07H21/02 ; C07H21/04 ; C12Q1/68

Abstract:
Methods and compositions are provided for the prevention or treatment of RSV infection in a human. The methods include administering one or more doses of a composition comprising an siRNA. The dose can be formulated for topical or parenteral administration. Topical administration includes administration as a nasal spray, or by inhalation of respirable particles or droplets. The siRNA comprises a sense strand of ALN-RSV01 and an antisense strand of ALN-RSV01.
Public/Granted literature
- US20120189555A1 METHODS AND COMPOSITIONS FOR PREVENTION OR TREATMENT OF RSV INFECTION Public/Granted day:2012-07-26
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