Invention Grant
- Patent Title: 9-(piperazinylalkyl) carbazoles as Bax-modulators
- Patent Title (中): 9-(哌嗪基烷基)咔唑作为Bax调节剂
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Application No.: US13225760Application Date: 2011-09-06
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Publication No.: US08410110B2Publication Date: 2013-04-02
- Inventor: Serge Halazy , Dennis Church , Bruno Antonsson , Agnes Bombrun , Patrick Gerber , Jean-Claude Martinou
- Applicant: Serge Halazy , Dennis Church , Bruno Antonsson , Agnes Bombrun , Patrick Gerber , Jean-Claude Martinou
- Applicant Address: CH Coinsins
- Assignee: Merck Serono SA
- Current Assignee: Merck Serono SA
- Current Assignee Address: CH Coinsins
- Agency: Oblon, Spivak, McClelland, Maier & Neustadt, L.L.P.
- Priority: EP99810944 19991018
- Main IPC: A61K31/497
- IPC: A61K31/497

Abstract:
Piperazine compounds for use as pharmaceutically active compounds and in pharmaceutical formulations that are useful for the treatment of disorders associated with apoptosis, including neurodegenerative disorders, diseases associated with polyglutamine tracts, epilepsy, ischemia, infertility, cardiovascular disorders, renal hypoxia, hepatitis and AIDS, where the piperazine compounds are represented by formula (I) and the terms R0, R1, R2, R3, k, l, m, n, and X are defined herein:
Public/Granted literature
- US20120040933A1 9-(PIPERAZINYLALKYL) CARBAZOLES AS BAX-MODULATORS Public/Granted day:2012-02-16
Information query
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