Invention Grant
US08410113B2 (2R)-1-(3-chloro-2-pyrazinyl)-2-methylpiperazine and salts thereof
失效
（2R）-1-（3-氯-2-吡嗪基）-2-甲基哌嗪及其盐
- Patent Title: (2R)-1-(3-chloro-2-pyrazinyl)-2-methylpiperazine and salts thereof
- Patent Title (中): （2R）-1-（3-氯-2-吡嗪基）-2-甲基哌嗪及其盐
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Application No.: US13234555Application Date: 2011-09-16
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Publication No.: US08410113B2Publication Date: 2013-04-02
- Inventor: Tom Fleck , Magnus Cernerud , Helena Lundström , Claes Löfström , Margit Pelcman , Alexander Paptchikhine , Emma Andersson , Alf Nygren
- Applicant: Magnus Cernerud , Helena Lundström , Claes Löfström , Margit Pelcman , Alexander Paptchikhine , Emma Andersson , Alf Nygren , Bruce Fleck
- Applicant Address: SE
- Assignee: Biovitrum AB (publ)
- Current Assignee: Biovitrum AB (publ)
- Current Assignee Address: SE
- Agency: Banner & Witcoff, Ltd.
- Priority: SE0201881 20020619; SE0202041 20020628; SE0202516 20020826
- Main IPC: C07D241/02
- IPC: C07D241/02 ; C07D403/00
Abstract:
The present invention relates to a process for the preparation of compounds which are therapeutically active in the central nervous system.In one aspect, the invention relates to a process for the preparation of compounds of the general formula (I): wherein HA is a pharmaceutically acceptable acid and R1-R4 are each independently selected from the group consisting of hydrogen, halogen, C1-C6-alkyl, C1-C6-alkoxy, and di-C1-C6-alkylamino-C2-C6-alkoxy. The invention also relates to the use of said compound to manufacture a medicament for the treatment of a serotonin-related disorder.
Public/Granted literature
- US20120010410A1 (2R)-1-(3-CHLORO-2-PYRAZINYL)-2-METHYLPIPERAZINE AND SALTS THEREOF Public/Granted day:2012-01-12
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