Invention Grant
US08410137B2 Thiophene-2-carboxamide derivatives, preparation thereof and therapeutic use thereof 有权
噻吩-2-甲酰胺衍生物,其制备及其治疗用途

Thiophene-2-carboxamide derivatives, preparation thereof and therapeutic use thereof
Abstract:
The subject matter of the invention is compounds corresponding to formula (I), in which: R1 and R2, together with the nitrogen atom to which they are attached, constitute a saturated heterocyclic radical containing from 4 to 7 atoms, which is preferably substituted; one of the two substituents R3 and R6 is a group Y-A-R9; Y is an oxygen atom or an —S(O)n′—, or —OSO2 group; A is an unsubstituted (C1-C4) alkylene group; R9 is an —OR19, —CH3, —NR19R20, —CONR19R20, —NR15COR19, —S(O)nR21, or —NR13SO2R21 group; —R10 is a hydrogen atom or a (C1-C4) alkyl group. The present invention also relates to the methods of preparation and the therapeutic uses of the compounds of formula (I).
Information query
Patent Agency Ranking
0/0