Invention Grant
US08410147B2 Method for treating diseases associated with alterations in cellular integrity using Rho kinase inhibitor compounds 失效
使用Rho激酶抑制剂化合物治疗与细胞完整性改变相关的疾病的方法

Method for treating diseases associated with alterations in cellular integrity using Rho kinase inhibitor compounds
Abstract:
This invention is directed to methods of preventing or treating diseases or conditions associated with alterations in cellular integrity including alterations in endothelial permeability, excessive cell proliferation or tissue remodeling. Particularly, this invention is directed to methods of treating diabetic nephropathy, malaria, or cancer. The method comprises identifying a subject in need of the treatment, and administering to the subject an effective amount of a novel rho kinase inhibitor compound to treat the disease.
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