Invention Grant
- Patent Title: Inhibitors of carnitine palmitoyltransferase and treating cancer
- Patent Title (中): 肉碱棕榈酰转移酶抑制剂和治疗癌症
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Application No.: US12530429Application Date: 2008-03-06
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Publication No.: US08410150B2Publication Date: 2013-04-02
- Inventor: Heinz W. Pauls , Peter Brent Sampson , Bryan T. Forrest , Radoslaw Laufer , Yong Liu , Miklos Feher , Yi Yao , Guohua Pan
- Applicant: Heinz W. Pauls , Peter Brent Sampson , Bryan T. Forrest , Radoslaw Laufer , Yong Liu , Miklos Feher , Yi Yao , Guohua Pan
- Applicant Address: CA Toronto
- Assignee: University Health Network
- Current Assignee: University Health Network
- Current Assignee Address: CA Toronto
- Agency: McCarter & English, LLP
- Agent Steven G. Davis; Wei Song
- International Application: PCT/CA2008/000440 WO 20080306
- International Announcement: WO2008/109991 WO 20080918
- Main IPC: C07D307/66
- IPC: C07D307/66 ; C07D333/32 ; C07D213/18 ; C07D233/70 ; C07D417/04 ; C07D263/36 ; C07D249/12 ; C07D261/10 ; C07D207/36 ; C07D275/03 ; C07D271/06 ; C07D285/08 ; C07C335/16 ; C07C327/40 ; C07C327/08 ; C07C311/10 ; C07C237/14 ; A61K31/34 ; A61K31/381 ; A61K31/4025 ; A61K31/40 ; A61K31/415 ; A61K31/4164 ; A61K31/4196 ; A61K31/42 ; A61K31/4245 ; A61K31/425 ; A61K31/433 ; A61K31/435 ; A61K31/64 ; A61K31/155
Abstract:
A CPT inhibitor compound is represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof: or a pharmaceutically acceptable salt thereof. A pharmaceutical composition comprises a compound represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof. A method of treating a subject having cancer comprises administering to the subject a therapeutically effective amount of a compound represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof.
Public/Granted literature
- US20100105900A1 INHIBITORS OF CARNITINE PALMITOYLTRANSFERASE AND TREATING CANCER Public/Granted day:2010-04-29
Information query
