Invention Grant
US08410189B2 Crosslinked polyalkyleneimine hydrogels with tunable degradation rates
有权
具有可降解降解速率的交联聚亚烷基亚胺水凝胶
- Patent Title: Crosslinked polyalkyleneimine hydrogels with tunable degradation rates
- Patent Title (中): 具有可降解降解速率的交联聚亚烷基亚胺水凝胶
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Application No.: US12371113Application Date: 2009-02-13
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Publication No.: US08410189B2Publication Date: 2013-04-02
- Inventor: Michael A. Carnahan , Jared D. G. Butlin
- Applicant: Michael A. Carnahan , Jared D. G. Butlin
- Applicant Address: US NC Durham
- Assignee: HyperBranch Medical Technology, Inc.
- Current Assignee: HyperBranch Medical Technology, Inc.
- Current Assignee Address: US NC Durham
- Agency: Foley Hoag LLP
- Agent Alan W. Steele
- Main IPC: A61K8/72
- IPC: A61K8/72 ; A61L24/00
Abstract:
One aspect of the present invention relates to methods of sealing a wound or tissue plane or filling a void space, or securing meshes, films or other devices within the body. In certain embodiments, the wound is an ophthalmic, pleural or dural wound, or a hernia repair mesh. Remarkably, disclosed herein is the discovery that the use of certain crosslinkers in combination with polyalkyleneimines at specific concentrations can result in hydrogels with tunable degradation properties.
Public/Granted literature
- US20090215923A1 Crosslinked Polyalkyleneimine Hydrogels with Tunable Degradation Rates Public/Granted day:2009-08-27
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