Invention Grant
US08410260B2 Double-stranded RNA oligonucleotides which inhibit tyrosinase expression
有权
抑制酪氨酸酶表达的双链RNA寡核苷酸
- Patent Title: Double-stranded RNA oligonucleotides which inhibit tyrosinase expression
- Patent Title (中): 抑制酪氨酸酶表达的双链RNA寡核苷酸
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Application No.: US12252125Application Date: 2008-10-15
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Publication No.: US08410260B2Publication Date: 2013-04-02
- Inventor: Christine Collin-Djangone , Jean-Thierry Simonnet
- Applicant: Christine Collin-Djangone , Jean-Thierry Simonnet
- Applicant Address: FR Paris
- Assignee: L'Oreal
- Current Assignee: L'Oreal
- Current Assignee Address: FR Paris
- Agency: Buchanan Ingersoll & Rooney PC
- Priority: FR0509658 20050921
- Main IPC: C07H21/02
- IPC: C07H21/02 ; C12N15/11 ; A61K9/126 ; A61K9/66
Abstract:
Novel double-stranded RNA oligonucleotides are useful for decreasing tyrosinase expression, have cosmetic and/or pharmaceutical applications, for example are useful skin depigmenting or anti-browning agents, and can be associated with cationic particles less than or equal to 1 μm in size, having a zeta potential of from 10 to 80 mV.
Public/Granted literature
- US20090081263A1 DOUBLE-STRANDED RNA OLIGONUCLEOTIDES WHICH INHIBIT TYROSINASE EXPRESSION Public/Granted day:2009-03-26
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