Invention Grant
US08410272B2 Pyrazolylbenzothiazole derivatives and their use as therapeutic agents
有权
吡唑基苯并噻唑衍生物及其用作治疗剂
- Patent Title: Pyrazolylbenzothiazole derivatives and their use as therapeutic agents
- Patent Title (中): 吡唑基苯并噻唑衍生物及其用作治疗剂
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Application No.: US12910744Application Date: 2010-10-22
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Publication No.: US08410272B2Publication Date: 2013-04-02
- Inventor: Zaihui Zhang , Timothy S Daynard , Shisen Wang , Xinyao Du , Gregory B Chopiuk , Jun Yan , Jianxin Chen , Serguei V Sviridov
- Applicant: Zaihui Zhang , Timothy S Daynard , Shisen Wang , Xinyao Du , Gregory B Chopiuk , Jun Yan , Jianxin Chen , Serguei V Sviridov
- Applicant Address: US CA Redwood City
- Assignee: Dermira (Canada), Inc.
- Current Assignee: Dermira (Canada), Inc.
- Current Assignee Address: US CA Redwood City
- Agency: Seed IP Law Group PLLC
- Agent Hai Han
- Main IPC: A61K31/437
- IPC: A61K31/437 ; C07D513/04
Abstract:
Pharmaceutical compositions and compounds are provided. The compounds of the invention have use as therapeutic agents, e.g., they demonstrate anti-proliferative, anti-inflammatory, anti-angiogenic, anti-migration activities. In one embodiment of the invention, formulations of the compounds in combination with a physiologically acceptable carrier are provided. The pharmaceutical formulations are useful in the treatment of, e.g., anti-inflammatory, renal, and hyperproliferative disorders. The compounds of the invention are pyrazolylbenzothiazole derivatives of the following formula (1) wherein X, R1, R2, R3 and R4 are described herein.
Public/Granted literature
- US20110178126A1 PYRAZOLYLBENZOTHIAZOLE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS Public/Granted day:2011-07-21
Information query
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