The present invention relates to a wireless communication system and, more particularly, to a method of transmitting and receiving frame in a wireless communication system.A method for transmitting a frame of a base station in a wireless communication system comprises the steps of transmitting a first region of the frame to a mobile station by using a first traffic to pilot ratio (hereinafter referred to as “TPR”); and transmitting a second region of the frame to the mobile station by using a second TPR, wherein the second TPR is different from the first TPR.