A method for dividing a subcarrier permutation zone in an Orthogonal Frequency Division Multiple Access system and an information configuration system for dividing a subcarrier permutation zone in the Orthogonal Frequency Division Multiple Access system are disclosed in the present invention. Wherein, the method for dividing the subcarrier permutation zone includes the following steps: a configuration unit performing configuration to a subcarrier permutation zone division information, and sending the subcarrier permutation zone division information to a configuration synchronization unit; the configuration synchronization unit calculating a configuration effective frame number, and sending the subcarrier permutation zone division information and the configuration effective frame number to a base station; the base station dividing the subcarrier permutation zone according to the subcarrier permutation zone division information and the configuration effective frame number. With the present invention, it can uniformly configure, in the whole network, the frame in which the subcarrier permutation zone appears and the position in the frame, so as to avoid the co-frequency interference between each of the adjacent zones.