A portable prescription sample transaction payment device has a substrate with a surface rendering corresponding to a prescription medical supply sample. Memory, in contact with the substrate, stores an identifier for the prescription medical supply sample, a quantity for the prescription medical supply sample, a dosage for the prescription medical supply sample, and an identifier for a patient. The memory also stores a pharmaceutical company account for a dispensing pharmacist to charge the cost of the prescription medical supply sample for payment to a dispensing pharmacist account to reimburse the dispensing pharmacist for the prescription medical supply sample. An image corresponding to the prescription medical supply sample is stored in the memory, as is an identifier for a prescribing medical practitioner prescribing the prescription medical supply sample to the patient.