An apparatus for securing cargo to a vehicle, and to tie-downs or sliders receivable in rails mounted to a bed, load deck, or other storage area of a vehicle, such as a pickup, sport utility vehicle, or trailer is described. A user may easily change, adjust or customize the tie-down locations to suit a desired application. The cargo securing system has a rail with a generally C-shaped cross section, the open end of the C-shape defining a slot which may run along the entire length of the rail. The C-shaped rail also defines a channel which may run along the entire length of the rail. A slider member may reside in the channel and include a foot or base portion and an integral elongate portion which may protrude through the slot in the rail. The slider member may include an integral tie-down location on the elongate portion.