An ultrasound therapy probe including a thin-profile therapy head for implementing therapeutic procedures in confined spaces. The thin-profile is achieved by incorporating a cooling fluid channel about a periphery of at least a portion of the housing. A therapy transducer is disposed in an inner volume of the housing, and fluid circulated through the peripheral cooling channel can be used to remove heat generated by the therapy transducer, without requiring bulky external cooling devices, such as balloons. The housing can include an acoustic lens portion, to enable the housing to be used with flat transducers and can also be configured to be used with concave transducers, and so that an acoustic lens is not required. Electrical connections can be made with conductors that extend through an elongate hollow handle.