Invention Grant
US08414857B2 Calcium phosphate granules of the hydroxyapatite type, their preparation process and their applications 失效
羟基磷灰石类型的磷酸钙颗粒,其制备方法及其应用

  • Patent Title: Calcium phosphate granules of the hydroxyapatite type, their preparation process and their applications
  • Patent Title (中): 羟基磷灰石类型的磷酸钙颗粒,其制备方法及其应用
  • Application No.: US12636028
    Application Date: 2009-12-11
  • Publication No.: US08414857B2
    Publication Date: 2013-04-09
  • Inventor: John GodberLorraine Leite
  • Applicant: John GodberLorraine Leite
  • Applicant Address: US NJ Cranbury
  • Assignee: Innophos, Inc.
  • Current Assignee: Innophos, Inc.
  • Current Assignee Address: US NJ Cranbury
  • Agent Joanne P. Will
  • Main IPC: C01B15/16
  • IPC: C01B15/16
Calcium phosphate granules of the hydroxyapatite type, their preparation process and their applications
Abstract:
The invention concerns calcium phosphates in granular form having an x-ray diffraction pattern characteristic of hydroxyapatite and good compressibility and flow properties in direct compression applications. The invention also concerns the method for preparing said granules characterized in that it comprises processing a suspension of brushite dicalcium phosphate having a certain particle-size distribution using a basic solution, and maintaining the pH at not less than 7.0 for a sufficient time interval to enable the transformation of the brushite calcium phosphate into hydroxyapatite calcium phosphate.
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