Invention Grant
US08414878B2 Irilis biopreparation based on bacillus-strain bacteria, bacillus subtilis and bacillus licheniformis contained therein
有权
基于芽孢杆菌菌株,枯草杆菌和地衣芽孢杆菌的伊利酵母生物制剂
- Patent Title: Irilis biopreparation based on bacillus-strain bacteria, bacillus subtilis and bacillus licheniformis contained therein
- Patent Title (中): 基于芽孢杆菌菌株,枯草杆菌和地衣芽孢杆菌的伊利酵母生物制剂
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Application No.: US11919356Application Date: 2005-04-28
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Publication No.: US08414878B2Publication Date: 2013-04-09
- Inventor: Irina Grigorievna Osipova , Irina Borisovna Sorokulova , Elena Aleksandrovna Vasilieva , Sergei Gennadievich Trofimov , Vera Franzevna Evlashkina , Elena Yurievna Haritonova , Sergei Eduardovich Sarkisov , Natalia Vasilievna Tereshkina , Yurii Igorevich Ostroumov , Aleksandr Nikolaevich Doronin , Marina Aleksandrovna Kulichizkaya , Aleksandr Aleksandrovich Matveev
- Applicant: Irina Grigorievna Osipova , Irina Borisovna Sorokulova , Elena Aleksandrovna Vasilieva , Sergei Gennadievich Trofimov , Vera Franzevna Evlashkina , Elena Yurievna Haritonova , Sergei Eduardovich Sarkisov , Natalia Vasilievna Tereshkina , Yurii Igorevich Ostroumov , Aleksandr Nikolaevich Doronin , Marina Aleksandrovna Kulichizkaya , Aleksandr Aleksandrovich Matveev
- Agency: Pauley Petersen & Erickson
- International Application: PCT/RU2005/000231 WO 20050428
- International Announcement: WO2006/115430 WO 20061102
- Main IPC: A01N63/00
- IPC: A01N63/00 ; A01N65/00 ; A61K39/02 ; A61K39/07 ; C12N1/00

Abstract:
A bioengineering, in particular to develop novel probiotic preparations based on Bacillus-strain bacteria, which can be used for preventing and treating infectious diseases and disbiosis of a human being, farm animals and birds. The novel strains of B. subtilis 07 (VKPM No. B-8611) and B. licheniformis 09 (VKPM No. B-8610) exhibit a broad spectrum of antagonistic activity, high proteolytic and amylase activity and a distinct ability in terms of a lysozim production. Such strains do not compete with each other but enter into synergistic relations in the form of an increased antagonistic action of the biopreparation. The inventive biopreparation comprises the B. subtilis 07 VKPM No. B-8611 and B. licheniformis 09 VKPM No. B-8610 strains and a protective medium. Such biopreparation can also contain a solvent and/or filler and exhibits an increased antagonistic activity with respect to a wide range of pathogenic and opportunistic pathogenic microorganisms and a resistance to quite a number of antibiotics.
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